Vinyl Chloride and PVC. No current information is available about the amount of vinyl chloride released from PVC pipes into water. CAS#: 75-01-4 Division of Toxicology and Environmental Medicine July 2006 . There are no other significant industrial sources of chemical contamination to which the 14 victims have been exposed. This toxic chemical is a known human carcinogen causing liver cancer, brain cancer and some cancers of the blood.
It has also been liked to brain and lung tumors and malignant haematopoietic lymphatic tumors. Vinyl chloride is an organochloride with the formula H 2 C=CHCl that is also called vinyl chloride monomer (VCM) or chloroethene.This colorless compound is an important industrial chemical chiefly used to produce the polymer polyvinyl chloride (PVC). But, Lake McCollum is an isolated community. Vinyl chloride is classified as Group 1 carcinogen by the IARC, meaning it is seen as a definite cause of cancer in humans. What You Can Do & How We Can Help. 1994; Guengerich 1994). How and where are people exposed to Vinyl Chloride? BLOG. Lyon, France 2008. Attorney At Law. PRACTICE AREAS. The Agency for Toxic Substances and Disease Registry describes vinyl chloride as having a sweet smell. Primary exposure to vinyl chloride occurs through inhalation. For some occupational cancers, the cause of the disease is accepted without much debate. Vinyl chloride is a carcinogen (a cancer-causing substance). It is also explosive and carcinogenic (cancer-causing). People exposed to high doses of ionizing radiation directed at the brain, the type of radiation used in radiation therapy, may develop a glioblastoma multiforme. This chemical compound has been identified as a human carcinogen, and long-term vinyl chloride exposure can lead to liver cancer, leukemia, and brain cancer. Vinyl chloride is most often used to produce PVC pipes. 20. Vinyl chloride has not been used at the plant since 1996. Br J … Steven H. Wodka. Experts for Rohm and Haas argue that the link is tenuous at best and concede only that vinyl chloride in high doses can cause a rare liver cancer … From the University of Louisville, Louisville, Kentucky (Dr Lewis, Dr Rempala); and Applied Epidemiology, … It can be dissolved into the air we breathe, becoming other potentially dangerous chemical compounds, or dissolved into the water we drink. Lawsuits and class actions have recently ended in multi-million dollar settlements for vinyl chloride exposure. Examples are asbestos and mesothelioma, or benzene and leukemia.
Prolonged exposure can cause cancer in the liver, brain, blood and lungs. Making a cancer cluster disappear The largest cluster of workplace-related brain tumors happened at this vinyl chloride plant now owned by Dow Chemical in Texas City, Texas. Vinyl Chloride is a toxic cancer-causing chemical that is used to make PVC. ( Morris 1998 ) In 2000, for the fourth time, an industry-sponsored study of VC epidemiology found an excess of brain cancer among exposed workers ( Doll 1988 ; Mundt et al. They are still cited by defendants in brain cancer cases, and are used to reassure workers about the safety of vinyl chloride and polyvinyl chloride. If you worked in the PVC, Vinyl Department before 1996, or suspect that you were exposed to vinyl chloride, see the … These have been the backbone of the vinyl industry’s defense that there is at best a “weak statistical correlation” between vinyl chloride exposure and brain cancer. One man from a plant in Louisville, Kentucky, developed angiosarcoma, a rare cancer, in his liver. Studies of overlapping cohorts in the United States have shown an excess mortality from brain cancer in vinyl chloride (VC)-exposed workers. We separated this plant from the large US cohort and re-analyzed the mortality experience. Vinyl chloride is mutagenic and is known to induce the formation of DNA adducts including 7-(2′-oxoethyl)guanine and exocyclic etheno adducts (Bartsch et al. Angiosarcoma attacks the lining of blood vessels, and can occur in any area of the body. Vinyl chloride exposure has been shown to increase the risk of a rare form of liver cancer called angiosarcoma. Meta-analysis of studies of occupational exposure to vinyl chloride in relation to cancer mortality.